Losartan for High Blood Pressure: Benefits, Side Effects, and Key Facts

What Is Losartan?

Losartan is a generic angiotensin II receptor blocker (ARB) that relaxes blood vessels, lowers blood pressure, and reduces strain on the heart and kidneys. It’s often prescribed when other medications (like ACE inhibitors) cause intolerable side effects, such as a persistent cough.

Key Uses:

• Hypertension: Lowers high blood pressure.

• Diabetic Kidney Protection: Prevents kidney damage in type 2 diabetes patients.

How Does Losartan Work?

Losartan blocks angiotensin II, a hormone that:

1. Narrows blood vessels, increasing blood pressure.

2. Promotes salt/water retention, further raising BP.

By inhibiting angiotensin II, Losartan:

• Relaxes blood vessels for smoother blood flow.

• Reduces fluid buildup, easing pressure on the heart and kidneys.

Losartan Dosage Guidelines

Condition     Typical Dosage     Notes

High Blood Pressure 50-100 mg once daily Start with 50 mg; adjust as needed.

Diabetic Kidney Disease 50-100 mg once daily Protects kidneys long-term.

Important Tips:

• Take at the same time daily (evening doses may reduce heart risks).

• Never double a missed dose. Skip it if close to the next scheduled time.

Losartan Side Effects

Common Side Effects:

• • Dizziness

  • Headache

  • Fatigue

  • Mild diarrhea

  • Elevated potassium levels

Serious Side Effects (Seek Immediate Help):

• • Yellowing skin/eyes (jaundice)

  • Swelling (face, throat, tongue)

  • Severe stomach pain or rash

  • Difficulty breathing

Who Should Avoid Losartan?

• Pregnant Women: Linked to birth defects.

• Breastfeeding Mothers: Passes into breast milk.

• Kidney Disease Patients: Can worsen non-diabetic kidney issues.

• Children Under 6: Not recommended.

Losartan Interactions & Precautions

Medications to Avoid:

• NSAIDs (e.g., ibuprofen): Increase kidney damage risk.

• Diuretics or Potassium Supplements: May spike potassium levels.

• Lithium or Blood Thinners: Alters drug effectiveness.

Food/Drink Tips:

• Avoid Low-Sodium Salt: High potassium content.

• Limit Alcohol: Can worsen dizziness.

FAQs About Losartan

Q: Does Losartan make you pee more?

A: No- unless you’re taking Hyzaar (Losartan + diuretic).

Q: How long until Losartan works?

A: Blood pressure drops in 3-6 weeks. Full kidney benefits take months.

Q: Can I stop Losartan if my BP improves?

A: No- always consult your doctor. Stopping abruptly risks rebound hypertension.

Q: Losartan vs. Lisinopril: Which is better?

A: Losartan: Fewer side effects (no cough), kidney protection.

Lisinopril (ACE inhibitor): This is Cheaper but may cause a dry cough.

Q: Is Losartan safe for kidneys?

A: Yes - for diabetics. Avoid if you have non-diabetic kidney disease.

Pros and Cons of Losartan

Pros     Cons

Fewer side effects than ACE inhibitors Raises potassium levels

Protects kidneys in diabetics Unsafe for pregnancy

Once - daily dosing Avoid with NSAIDs

Losartan is a versatile, well-tolerated medication for hypertension and diabetic kidney care. While side effects are rare, regular monitoring of blood pressure, kidney function, and potassium levels is crucial. Never self-adjust your dose, and work with your doctor to optimize your treatment plan.

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