The heart is a marvel of biological engineering, tirelessly pumping blood to sustain life. To truly appreciate its function, it’s essential to understand the cardiac cycle - the sequence of events that occur with each heartbeat. Building on our knowledge of the heart’s anatomy and blood flow, let’s dive into the intricate steps of the cardiac cycle, where pressure changes, valve movements, and electrical conduction work in harmony to keep us alive.
The cardiac cycle consists of two main phases: diastole and systole. Diastole is the relaxation phase, while systole is the contraction phase. These phases ensure that blood flows smoothly through the heart and into the circulatory system. Let’s break it down step by step.
Diastole is the phase when the heart is relaxed, allowing blood to fill its chambers. During this time:
The ventricles (the heart’s lower chambers) are in a low-pressure state because they’re not contracting.
Blood from the body enters the right atrium via the superior and inferior vena cava, while oxygenated blood from the lungs flows into the left atrium through the pulmonary veins.
As the atria fill with blood, atrial pressure increases. Eventually, this pressure surpasses the low pressure in the ventricles, causing the tricuspid valve (between the right atrium and ventricle) and the mitral valve (between the left atrium and ventricle) to open.
Blood flows passively from the atria into the ventricles, driven solely by pressure differences - no contraction is needed yet.
As the ventricles continue to fill, the heart’s conduction system kicks into gear. Here’s how it works:
The sinoatrial (SA) node, located in the right atrium, generates an electrical impulse. This impulse spreads through the atria, causing them to contract.
This atrial contraction further increases atrial pressure, pushing additional blood into the ventricles - a process known as atrial kick.
The electrical impulse then reaches the atrioventricular (AV) node, which slows down the signal. This delay ensures that the atria have enough time to fully contract and empty their blood into the ventricles before the ventricles themselves contract.
Once the atria have done their job, the focus shifts to the ventricles. This marks the beginning of systole, the contraction phase:
The electrical impulse travels from the AV node through the bundle of His, bundle branches, and Purkinje fibers, causing the ventricles to depolarize and contract.
As the ventricles contract, ventricular pressure rises sharply. When this pressure exceeds the atrial pressure, the tricuspid and mitral valves close, preventing backflow into the atria.
With the valves closed, ventricular pressure continues to rise until it surpasses the pressure in the pulmonary artery and aorta. This forces the pulmonary valve and aortic valve to open, allowing blood to be ejected from the right ventricle into the pulmonary artery (toward the lungs) and from the left ventricle into the aorta (to the rest of the body).
As blood exits the ventricles, their pressure begins to drop. Eventually:
The ventricles repolarize and relax, causing their pressure to fall below that of the pulmonary artery and aorta. This leads to the closure of the pulmonary and aortic valves, preventing backflow.
With the valves closed, the heart returns to diastole, and the cycle begins anew. Blood once again fills the atria, and the process repeats.
The cardiac cycle is a perfect example of the heart’s efficiency and precision. Every step - from the pressure changes that drive blood flow to the electrical signals that coordinate contractions - is meticulously timed to ensure optimal function. This cycle repeats approximately 60-100 times per minute in a healthy adult, demonstrating the heart’s incredible endurance and reliability.